Even on a tight schedule, Brancacci Chapel (Santa Maria del Carmine) earns the hours.
Allow 45 minutes (incl. timed slot).
Masaccio's Expulsion from Eden and Tribute Money here are where Renaissance painting effectively begins — a pilgrimage for anyone who cares about art history, freshly restored and seen up close from a viewing platform. The catch: entry is timed to small groups and must be booked, it's a single room across the river, and the significance is lost on casual visitors. A specialist's WORTH_IT, a generalist's skip.